Oxidized plasma albumin promotes platelet-endothelial crosstalk and endothelial tissue factor expression

Plasma advanced oxidation protein products (AOPPs), a class of pro-inflammatory pathogenic mediators, accumulate in subjects with chronic kidney disease. Whether AOPPs contribute to coagulation abnormalities, which are frequently seen in uremic patients, is unknown. Here we report that AOPPs activat...

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Publicat a:Sci Rep
Autors principals: Pasterk, Lisa, Lemesch, Sandra, Leber, Bettina, Trieb, Markus, Curcic, Sanja, Stadlbauer, Vanessa, Schuligoi, Rufina, Schicho, Rudolf, Heinemann, Akos, Marsche, Gunther
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764952/
https://ncbi.nlm.nih.gov/pubmed/26905525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22104
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