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Oxidized plasma albumin promotes platelet-endothelial crosstalk and endothelial tissue factor expression

Plasma advanced oxidation protein products (AOPPs), a class of pro-inflammatory pathogenic mediators, accumulate in subjects with chronic kidney disease. Whether AOPPs contribute to coagulation abnormalities, which are frequently seen in uremic patients, is unknown. Here we report that AOPPs activat...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Pasterk, Lisa, Lemesch, Sandra, Leber, Bettina, Trieb, Markus, Curcic, Sanja, Stadlbauer, Vanessa, Schuligoi, Rufina, Schicho, Rudolf, Heinemann, Akos, Marsche, Gunther
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764952/
https://ncbi.nlm.nih.gov/pubmed/26905525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22104
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