Oxidized plasma albumin promotes platelet-endothelial crosstalk and endothelial tissue factor expression

Plasma advanced oxidation protein products (AOPPs), a class of pro-inflammatory pathogenic mediators, accumulate in subjects with chronic kidney disease. Whether AOPPs contribute to coagulation abnormalities, which are frequently seen in uremic patients, is unknown. Here we report that AOPPs activat...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Pasterk, Lisa, Lemesch, Sandra, Leber, Bettina, Trieb, Markus, Curcic, Sanja, Stadlbauer, Vanessa, Schuligoi, Rufina, Schicho, Rudolf, Heinemann, Akos, Marsche, Gunther
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764952/
https://ncbi.nlm.nih.gov/pubmed/26905525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22104
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