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Evidence that central pathways that mediate defecation utilize ghrelin receptors but do not require endogenous ghrelin

In laboratory animals and in human, centrally penetrant ghrelin receptor agonists, given systemically or orally, cause defecation. Animal studies show that the effect is due to activation of ghrelin receptors in the spinal lumbosacral defecation centers. However, it is not known whether there is a p...

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Detalhes bibliográficos
Publicado no:Physiol Rep
Main Authors: Pustovit, Ruslan V, Callaghan, Brid, Ringuet, Mitchell T, Kerr, Nicole F, Hunne, Billie, Smyth, Ian M, Pietra, Claudio, Furness, John B.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555902/
https://ncbi.nlm.nih.gov/pubmed/28801520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13385
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