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Evidence that central pathways that mediate defecation utilize ghrelin receptors but do not require endogenous ghrelin

In laboratory animals and in human, centrally penetrant ghrelin receptor agonists, given systemically or orally, cause defecation. Animal studies show that the effect is due to activation of ghrelin receptors in the spinal lumbosacral defecation centers. However, it is not known whether there is a p...

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Dades bibliogràfiques
Publicat a:Physiol Rep
Autors principals: Pustovit, Ruslan V, Callaghan, Brid, Ringuet, Mitchell T, Kerr, Nicole F, Hunne, Billie, Smyth, Ian M, Pietra, Claudio, Furness, John B.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555902/
https://ncbi.nlm.nih.gov/pubmed/28801520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13385
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