The Orexigenic Effect of Ghrelin Is Mediated through Central Activation of the Endogenous Cannabinoid System

INTRODUCTION: Ghrelin and cannabinoids stimulate appetite, this effect possibly being mediated by the activation of hypothalamic AMP-activated protein kinase (AMPK), a key enzyme in appetite and metabolism regulation. The cannabinoid receptor type 1 (CB1) antagonist rimonabant can block the orexigen...

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Main Authors: Kola, Blerina, Farkas, Imre, Christ-Crain, Mirjam, Wittmann, Gábor, Lolli, Francesca, Amin, Faisal, Harvey-White, Judith, Liposits, Zsolt, Kunos, George, Grossman, Ashley B., Fekete, Csaba, Korbonits, Márta
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2008
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258435/
https://ncbi.nlm.nih.gov/pubmed/18335063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001797
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