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Metabolic Disorder Dysfunction in Parkinson’s Disease: Bioenergetics, Redox Homeostasis and Central Carbon Metabolism

The loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc) and the accumulation of protein inclusions (Lewy bodies) are the pathological hallmarks of Parkinson’s disease (PD). PD is triggered by genetic alterations, environmental/occupational exposures and aging. However, the exac...

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Bibliographic Details
Published in:Brain Res Bull
Main Authors: Anandhan, Annadurai, Jacome, Maria S., Lei, Shulei, Hernandez-Franco, Pablo, Pappa, Aglaia, Panayiotidis, Mihalis I, Powers, Robert, Franco, Rodrigo
Format: Artigo
Language:Inglês
Published: 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555796/
https://ncbi.nlm.nih.gov/pubmed/28341600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainresbull.2017.03.009
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