Metabolic Disorder Dysfunction in Parkinson’s Disease: Bioenergetics, Redox Homeostasis and Central Carbon Metabolism

The loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc) and the accumulation of protein inclusions (Lewy bodies) are the pathological hallmarks of Parkinson’s disease (PD). PD is triggered by genetic alterations, environmental/occupational exposures and aging. However, the exac...

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Publicado en:Brain Res Bull
Autores principales: Anandhan, Annadurai, Jacome, Maria S., Lei, Shulei, Hernandez-Franco, Pablo, Pappa, Aglaia, Panayiotidis, Mihalis I, Powers, Robert, Franco, Rodrigo
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555796/
https://ncbi.nlm.nih.gov/pubmed/28341600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainresbull.2017.03.009
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