Metabolic Disorder Dysfunction in Parkinson’s Disease: Bioenergetics, Redox Homeostasis and Central Carbon Metabolism

The loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc) and the accumulation of protein inclusions (Lewy bodies) are the pathological hallmarks of Parkinson’s disease (PD). PD is triggered by genetic alterations, environmental/occupational exposures and aging. However, the exac...

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Detalhes bibliográficos
Publicado no:Brain Res Bull
Main Authors: Anandhan, Annadurai, Jacome, Maria S., Lei, Shulei, Hernandez-Franco, Pablo, Pappa, Aglaia, Panayiotidis, Mihalis I, Powers, Robert, Franco, Rodrigo
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555796/
https://ncbi.nlm.nih.gov/pubmed/28341600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainresbull.2017.03.009
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