Metabolic Disorder Dysfunction in Parkinson’s Disease: Bioenergetics, Redox Homeostasis and Central Carbon Metabolism

The loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc) and the accumulation of protein inclusions (Lewy bodies) are the pathological hallmarks of Parkinson’s disease (PD). PD is triggered by genetic alterations, environmental/occupational exposures and aging. However, the exac...

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Publicat a:Brain Res Bull
Autors principals: Anandhan, Annadurai, Jacome, Maria S., Lei, Shulei, Hernandez-Franco, Pablo, Pappa, Aglaia, Panayiotidis, Mihalis I, Powers, Robert, Franco, Rodrigo
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555796/
https://ncbi.nlm.nih.gov/pubmed/28341600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainresbull.2017.03.009
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