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Autoantibodies against GPIHBP1 as a Cause of Hypertriglyceridemia
BACKGROUND: A protein that is expressed on capillary endothelial cells, called GPIHBP1 (glycosylphosphatidylinositol-anchored high-density lipoprotein binding protein 1), binds lipoprotein lipase and shuttles it to its site of action in the capillary lumen. A deficiency in GPIHBP1 prevents lipoprote...
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| Pubblicato in: | N Engl J Med |
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| Autori principali: | , , , , , , , , , , , , , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5555413/ https://ncbi.nlm.nih.gov/pubmed/28402248 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1611930 |
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