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The interaction between σ(70) and the β-flap of Escherichia coli RNA polymerase inhibits extension of nascent RNA during early elongation
The σ-subunit of bacterial RNA polymerase (RNAP) is required for promoter-specific transcription initiation. This function depends on specific intersubunit interactions that occur when σ associates with the RNAP core enzyme to form RNAP holoenzyme. Among these interactions, that between conserved re...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2005
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC555512/ https://ncbi.nlm.nih.gov/pubmed/15761057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409850102 |
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