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A Critical Role of Downstream RNA Polymerase-Promoter Interactions in the Formation of Initiation Complex

Nucleation of promoter melting in bacteria is coupled with RNA polymerase (RNAP) binding to a conserved −10 promoter element located at the upstream edge of the transcription bubble. The mechanism of downstream propagation of the transcription bubble to include the transcription start site is unclea...

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Hlavní autoři: Mekler, Vladimir, Minakhin, Leonid, Severinov, Konstantin
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121404/
https://ncbi.nlm.nih.gov/pubmed/21525530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.247080
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