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Lack of evidence for conserved secondary structure in long noncoding RNAs
Many functional RNAs have an evolutionarily conserved secondary structure. Conservation of RNA base pairing induces pairwise covariations in sequence alignments. We developed a computational method that quantitatively tests whether covariation analysis supports the presence of a conserved RNA second...
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| Publicado no: | Nat Methods |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5554622/ https://ncbi.nlm.nih.gov/pubmed/27819659 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.4066 |
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