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The ER structural protein Rtn4A stabilizes and enhances signaling through the receptor tyrosine kinase ErbB3

ErbB3 and ErbB4 are receptor tyrosine kinases that are activated by the neuregulin (NRG) family of growth factors. These receptors govern various developmental processes, and their dysregulation contributes to several human disease states. The abundance of ErbB3 and ErbB4, and thus signaling through...

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Detalhes bibliográficos
Publicado no:Sci Signal
Main Authors: Hatakeyama, Jason, Wald, Jessica H., Rafidi, Hanine, Cuevas, Antonio, Sweeney, Colleen, Carraway, Kermit L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5554593/
https://ncbi.nlm.nih.gov/pubmed/27353365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aaf1604
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