The ER structural protein Rtn4A stabilizes and enhances signaling through the receptor tyrosine kinase ErbB3

ErbB3 and ErbB4 are receptor tyrosine kinases that are activated by the neuregulin (NRG) family of growth factors. These receptors govern various developmental processes, and their dysregulation contributes to several human disease states. The abundance of ErbB3 and ErbB4, and thus signaling through...

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Bibliographic Details
Published in:Sci Signal
Main Authors: Hatakeyama, Jason, Wald, Jessica H., Rafidi, Hanine, Cuevas, Antonio, Sweeney, Colleen, Carraway, Kermit L.
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5554593/
https://ncbi.nlm.nih.gov/pubmed/27353365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aaf1604
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