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Conformational changes in receptor tyrosine kinase signaling: an ErbB garden of delights

The ErbB family of receptor tyrosine kinases plays important roles in cell proliferation, differentiation, and apoptosis. Recent structural studies of these receptors have demonstrated dramatic conformational effects that are critical to their ligand binding and activation, and have shown that these...

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Hlavní autoři: Carraway, Kermit L, Kozloski, Goldi A
Médium: Artigo
Jazyk:Inglês
Vydáno: Biology Reports Ltd 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847299/
https://ncbi.nlm.nih.gov/pubmed/20357902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3410/B1-72
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