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Conformational changes in receptor tyrosine kinase signaling: an ErbB garden of delights

The ErbB family of receptor tyrosine kinases plays important roles in cell proliferation, differentiation, and apoptosis. Recent structural studies of these receptors have demonstrated dramatic conformational effects that are critical to their ligand binding and activation, and have shown that these...

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Detalhes bibliográficos
Main Authors: Carraway, Kermit L, Kozloski, Goldi A
Formato: Artigo
Idioma:Inglês
Publicado em: Biology Reports Ltd 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847299/
https://ncbi.nlm.nih.gov/pubmed/20357902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3410/B1-72
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