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Mechanistic and Signaling Analysis of Muc4-ErbB2 Signaling Module: New Insights into the Mechanism of Ligand-Independent ErbB2 Activity
The membrane mucin Muc4 is aberrantly expressed in numerous epithelial carcinomas and is currently used as a cancer diagnostic and prognostic tool. Muc4 can also potentiate signal transduction by modulating differential ErbB2 phosphorylation in the absence and in the presence of the ErbB3 soluble li...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2897936/ https://ncbi.nlm.nih.gov/pubmed/20432461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.22163 |
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