Statin use at the time of initiation of androgen deprivation therapy and time to progression in patients with hormone-sensitive prostate cancer

IMPORTANCE: Statin use has been associated with improved prostate cancer outcomes. Dehydroepiandrosterone sulfate (DHEAS) is a precursor of testosterone and a substrate for SLCO2B1, an organic anionic transporter. We previously demonstrated that genetic variants of SLCO2B1 correlated with time to pr...

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Veröffentlicht in:JAMA Oncol
Hauptverfasser: Harshman, Lauren C., Wang, Xiaodong, Nakabayashi, Mari, Xie, Wanling, Valenca, Loana, Werner, Lillian, Yu, Yongjiang, Kantoff, Aaron M., Sweeney, Christopher J., Mucci, Lorelei A., Pomerantz, Mark, Lee, Gwo-Shu Mary, Kantoff, Philip W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5554437/
https://ncbi.nlm.nih.gov/pubmed/26181260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2015.0829
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