Combined antiangiogenic and anti–PD-L1 therapy stimulates tumor immunity through HEV formation

Inhibitors of VEGF (vascular endothelial growth factor)/VEGFR2 (vascular endothelial growth factor receptor 2) are commonly used in the clinic, but their beneficial effects are only observed in a subset of patients and limited by induction of diverse relapse mechanisms. We describe the up-regulation...

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Vydáno v:Sci Transl Med
Hlavní autoři: Allen, Elizabeth, Jabouille, Arnaud, Rivera, Lee B., Lodewijckx, Inge, Missiaen, Rindert, Steri, Veronica, Feyen, Kevin, Tawney, Jaime, Hanahan, Douglas, Michael, Iacovos P., Bergers, Gabriele
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5554432/
https://ncbi.nlm.nih.gov/pubmed/28404866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aak9679
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