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HIF1α regulates glioma chemosensitivity through the transformation between differentiation and dedifferentiation in various oxygen levels

Chemotherapy plays a significant role in glioma treatment; however, it has limited effectiveness in extending the life expectancies of glioma patients. Traditional studies have attributed this lack of efficacy to glioma stem cells (GSCs) and their high resistance to chemotherapy, and hypoxia worsens...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Sci Rep
Κύριοι συγγραφείς: Wang, Pan, Wan, Wenwu, Xiong, Shuanglong, Wang, Junwei, Zou, Dewei, Lan, Chuan, Yu, Shuangjiang, Liao, Bin, Feng, Hua, Wu, Nan
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Nature Publishing Group UK 2017
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5554160/
https://ncbi.nlm.nih.gov/pubmed/28801626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06086-2
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