Epoxyeicosatrienoic Acid Activation of the Wnt1 Canonical Pathway Mediated by an Increase in Heme Oxygenase 1, Reduces Infarct Size and Cardiac Dysfunction

Myocardial infarction (MI) is complicated by ventricular fibrosis and associated diastolic and systolic failure. Emerging studies implicate Wnt1 signaling in the formation of new blood vessels. Epoxyeicosatrienoic acids (EETs)-mediated up-regulation of heme oxygenase-1 (HO-1) protects against the de...

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Publicado en:Prostaglandins Other Lipid Mediat
Main Authors: Cao, Jian, Tsenovoy, Peter L., Thompson, Ellen A., Falck, John R., Touchon, Robert, Sodhi, Komal, Shapiro, Joseph I., Kappas, Attallah, Abraham, Nader G.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5553685/
https://ncbi.nlm.nih.gov/pubmed/25677507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prostaglandins.2015.01.002
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