Epoxyeicosatrienoic Acid Activation of the Wnt1 Canonical Pathway Mediated by an Increase in Heme Oxygenase 1, Reduces Infarct Size and Cardiac Dysfunction

Myocardial infarction (MI) is complicated by ventricular fibrosis and associated diastolic and systolic failure. Emerging studies implicate Wnt1 signaling in the formation of new blood vessels. Epoxyeicosatrienoic acids (EETs)-mediated up-regulation of heme oxygenase-1 (HO-1) protects against the de...

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Gepubliceerd in:Prostaglandins Other Lipid Mediat
Hoofdauteurs: Cao, Jian, Tsenovoy, Peter L., Thompson, Ellen A., Falck, John R., Touchon, Robert, Sodhi, Komal, Shapiro, Joseph I., Kappas, Attallah, Abraham, Nader G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5553685/
https://ncbi.nlm.nih.gov/pubmed/25677507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prostaglandins.2015.01.002
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