Increased heme-oxygenase 1 expression in mesenchymal stem cell-derived adipocytes decreases differentiation and lipid accumulation via upregulation of the canonical Wnt signaling cascade

INTRODUCTION: Heme oxygenase (HO), a major cytoprotective enzyme, attenuates oxidative stress and obesity. The canonical Wnt signaling cascade plays a pivotal role in the regulation of adipogenesis. The present study examined the interplay between HO-1and the Wnt canonical pathway in the modulation...

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Detalhes bibliográficos
Main Authors: Vanella, Luca, Sodhi, Komal, Kim, Dong Hyun, Puri, Nitin, Maheshwari, Mani, Hinds, Terry D, Bellner, Lars, Goldstein, Dov, Peterson, Stephen J, Shapiro, Joseph I, Abraham, Nader G
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706794/
https://ncbi.nlm.nih.gov/pubmed/23497794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/scrt176
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