Heme Oxygenase (HO-1) Rescue of Adipocyte Dysfunction in HO-2 Deficient Mice via Recruitment of Epoxyeicosatrienoic Acids (EETs) and Adiponectin

BACKGROUND/AIMS: HO-1 and EETs are functionally linked and their interactions influence body weight, insulin sensitivity, and serum levels of inflammatory cytokines in metabolic syndrome phenotype of HO-2 null mice. The HO-2 isozyme is essential for regulating physiological levels of ROS. Recent stu...

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Autors principals: Burgess, Angela P.H., Vanella, Luca, Bellner, Lars, Gotlinger, Katherine, Falck, John R., Abraham, Nader G., Schwartzman, Michal L., Kappas, Attallah
Format: Artigo
Idioma:Inglês
Publicat: S. Karger AG 2012
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Original Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711769/
https://ncbi.nlm.nih.gov/pubmed/22415079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000337591
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