Epoxyeicosatrienoic Acid Agonist Rescues the Metabolic Syndrome Phenotype of HO-2-Null Mice

Heme oxygenase (HO) and cytochrome P450 (P450)-derived epoxyeicosatrienoic acids (EETs) participate in vascular protection, and recent studies suggest these two systems are functionally linked. We examined the consequences of HO deficiency on P450-derived EETs with regard to body weight, adiposity,...

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Detalhes bibliográficos
Main Authors: Sodhi, Komal, Inoue, Kazuyoshi, Gotlinger, Katherine H., Canestraro, Martina, Vanella, Luca, Kim, Dong Hyun, Manthati, Vijay L., Koduru, Sreenivasulu Reddy, Falck, John R., Schwartzman, Michal L., Abraham, Nader G.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2009
Assuntos:
Endocrine and Diabetes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2784709/
https://ncbi.nlm.nih.gov/pubmed/19717790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.157545
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