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Hypothalamic-specific proopiomelanocortin-deficiency reduces alcohol drinking in male and female mice

Opioid receptor antagonist naltrexone reduces alcohol consumption and relapse in both humans and rodents. The present study investigated whether hypothalamic proopiomelanocortin (POMC) neurons (producing beta-endorphin and melanocortins) play a role in alcohol drinking behaviors. Both male and femal...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Genes Brain Behav
Prif Awduron: Zhou, Yan, Rubinstein, Marcelo, Low, Malcolm J, Kreek, Mary Jeanne
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5553441/
https://ncbi.nlm.nih.gov/pubmed/27870313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/gbb.12362
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