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Hypothalamic-specific proopiomelanocortin-deficiency reduces alcohol drinking in male and female mice

Opioid receptor antagonist naltrexone reduces alcohol consumption and relapse in both humans and rodents. The present study investigated whether hypothalamic proopiomelanocortin (POMC) neurons (producing beta-endorphin and melanocortins) play a role in alcohol drinking behaviors. Both male and femal...

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Detalhes bibliográficos
Publicado no:Genes Brain Behav
Main Authors: Zhou, Yan, Rubinstein, Marcelo, Low, Malcolm J, Kreek, Mary Jeanne
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5553441/
https://ncbi.nlm.nih.gov/pubmed/27870313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/gbb.12362
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