Novel giardicidal compounds bearing proton pump inhibitor scaffold proceeding through triosephosphate isomerase inactivation

Giardiasis is a worldwide parasitic disease that affects mainly children and immunosuppressed people. Side effects and the emergence of resistance over current used drugs make imperative looking for new antiparasitics through discovering of new biological targets and designing of novel drugs. Recent...

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Publicat a:Sci Rep
Autors principals: Hernández-Ochoa, B., Navarrete-Vázquez, G., Nava-Zuazo, C., Castillo-Villanueva, A., Méndez, S. T., Torres-Arroyo, A., Gómez-Manzo, S., Marcial-Quino, J., Ponce-Macotela, M., Rufino-González, Y., Martínez-Gordillo, M., Palencia-Hernández, G., Esturau-Escofet, N., Calderon-Jaimes, E., Oria-Hernández, J., Reyes-Vivas, H.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5552691/
https://ncbi.nlm.nih.gov/pubmed/28798383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07612-y
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