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HBEGF promotes gliomagenesis in the context of Ink4a/Arf and Pten loss
Heparin-binding epidermal growth factor (EGF)-like growth factor (HBEGF) is a ligand for the epidermal growth factor receptor (EGFR), one of the most commonly amplified receptor tyrosine kinases (RTK) in glioblastoma. While HBEGF has been found to be expressed in a subset of malignant gliomas, its s...
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| Pubblicato in: | Oncogene |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5552427/ https://ncbi.nlm.nih.gov/pubmed/28368403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2017.83 |
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