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Unexpected sequences and structures of mtDNA required for efficient transcription from the first heavy-strand promoter
Human mtDNA contains three promoters, suggesting a need for differential expression of the mitochondrial genome. Studies of mitochondrial transcription have used a reductionist approach, perhaps masking differential regulation. Here we evaluate transcription from light-strand (LSP) and heavy-strand...
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Publicado no: | eLife |
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Main Authors: | , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
eLife Sciences Publications, Ltd
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5552277/ https://ncbi.nlm.nih.gov/pubmed/28745586 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.27283 |
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