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Double-Strand Breaks of Mouse Muscle mtDNA Promote Large-Deletions Similar to Multiple mtDNA Deletions in Humans
Mitochondrial DNA (mtDNA) deletions are a common cause of mitochondrial disorders and have been found to accumulate during normal aging. Despite the fact that hundreds of deletions have been characterized at the molecular level, their mechanisms of genesis are unknown. We tested the effect of double...
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| Main Authors: | , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
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2005
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1242110/ https://ncbi.nlm.nih.gov/pubmed/15703189 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddi082 |
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