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IRF6 expression in basal epithelium partially rescues Irf6 knockout mice
BACKGROUND: Mutations in IRF6, CHUK (IKKA) and RIPK4 can lead to a disease spectrum that includes cutaneous, limb and craniofacial malformations. Loss of these alleles in the mouse leads to perinatal lethality and severe cutaneous, limb and craniofacial defects. Genetic rescue in the mouse has been...
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| Publicado no: | Dev Dyn |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5552062/ https://ncbi.nlm.nih.gov/pubmed/28643456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.24537 |
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