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Intercellular Genetic Interaction Between Irf6 and Twist1 during Craniofacial Development
Interferon Regulatory Factor 6 (IRF6) and TWIST1 are transcription factors necessary for craniofacial development. Human genetic studies showed that mutations in IRF6 lead to cleft lip and palate and mandibular abnormalities. In the mouse, we found that loss of Irf6 causes craniosynostosis and mandi...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5540929/ https://ncbi.nlm.nih.gov/pubmed/28769044 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06310-z |
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