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Evolutionary Dynamics and Significance of Multiple Subclonal Mutations in Cancer

For the last 40 years the authors have collaborated on trying to understand the complexities of human cancer by formulating testable mathematical models that are based on mutation accumulation in human malignancies. We summarize the concepts encompassed by multiple mutations in human cancers in the...

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Библиографические подробности
Опубликовано в: :DNA Repair (Amst)
Главные авторы: Beckman, Robert A., Loeb, Lawrence A.
Формат: Artigo
Язык:Inglês
Опубликовано: 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5551892/
https://ncbi.nlm.nih.gov/pubmed/28652129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2017.06.002
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