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The influence of subclonal resistance mutations on targeted cancer therapy

Clinical oncology is being revolutionized by the increasing use of molecularly targeted therapies. This paradigm holds great promise for improving cancer treatment; however, allocating specific therapies to the patients who are most likely to derive a durable benefit continues to represent a conside...

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Detalhes bibliográficos
Publicado no:Nat Rev Clin Oncol
Main Authors: Schmitt, Michael W., Loeb, Lawrence A., Salk, Jesse J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4838548/
https://ncbi.nlm.nih.gov/pubmed/26483300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrclinonc.2015.175
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