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The influence of subclonal resistance mutations on targeted cancer therapy

Clinical oncology is being revolutionized by the increasing use of molecularly targeted therapies. This paradigm holds great promise for improving cancer treatment; however, allocating specific therapies to the patients who are most likely to derive a durable benefit continues to represent a conside...

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Detalles Bibliográficos
Publicado en:Nat Rev Clin Oncol
Autores principales: Schmitt, Michael W., Loeb, Lawrence A., Salk, Jesse J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4838548/
https://ncbi.nlm.nih.gov/pubmed/26483300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrclinonc.2015.175
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