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Evolutionary Dynamics and Significance of Multiple Subclonal Mutations in Cancer

For the last 40 years the authors have collaborated on trying to understand the complexities of human cancer by formulating testable mathematical models that are based on mutation accumulation in human malignancies. We summarize the concepts encompassed by multiple mutations in human cancers in the...

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Bibliographic Details
Published in:DNA Repair (Amst)
Main Authors: Beckman, Robert A., Loeb, Lawrence A.
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5551892/
https://ncbi.nlm.nih.gov/pubmed/28652129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2017.06.002
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