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Evolutionary Dynamics and Significance of Multiple Subclonal Mutations in Cancer

For the last 40 years the authors have collaborated on trying to understand the complexities of human cancer by formulating testable mathematical models that are based on mutation accumulation in human malignancies. We summarize the concepts encompassed by multiple mutations in human cancers in the...

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Detalhes bibliográficos
Publicado no:DNA Repair (Amst)
Main Authors: Beckman, Robert A., Loeb, Lawrence A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5551892/
https://ncbi.nlm.nih.gov/pubmed/28652129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2017.06.002
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