The G protein–coupled receptor GPR31 promotes membrane association of KRAS

The product of the KRAS oncogene, KRAS4B, promotes tumor growth when associated with the plasma membrane (PM). PM association is mediated, in part, by farnesylation of KRAS4B, but trafficking of nascent KRAS4B to the PM is incompletely understood. We performed a genome-wide screen to identify genes...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:J Cell Biol
Autori principali: Fehrenbacher, Nicole, Tojal da Silva, Israel, Ramirez, Craig, Zhou, Yong, Cho, Kwang-Jin, Kuchay, Shafi, Shi, Jie, Thomas, Susan, Pagano, Michele, Hancock, John F., Bar-Sagi, Dafna, Philips, Mark R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2017
Soggetti:
Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5551702/
https://ncbi.nlm.nih.gov/pubmed/28619714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201609096
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi