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The G protein–coupled receptor GPR31 promotes membrane association of KRAS
The product of the KRAS oncogene, KRAS4B, promotes tumor growth when associated with the plasma membrane (PM). PM association is mediated, in part, by farnesylation of KRAS4B, but trafficking of nascent KRAS4B to the PM is incompletely understood. We performed a genome-wide screen to identify genes...
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| Publicado no: | J Cell Biol |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5551702/ https://ncbi.nlm.nih.gov/pubmed/28619714 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201609096 |
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