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Targeting RAS – will GPR31 deliver us a new path forward?
Effective anti-rat sarcoma viral oncogene (RAS) therapies have remained the holy grail of cancer treatment. Mutant Kirsten rat sarcoma viral oncogene homolog (KRAS) sustains tumorigenesis when linked to the plasma membrane (PM). The G protein-coupled receptor 31 (GPR31) is now identified to mediate...
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| 發表在: | Mol Cell Oncol |
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| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Taylor & Francis
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5706936/ https://ncbi.nlm.nih.gov/pubmed/29209647 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2017.1359228 |
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