Binding Properties of the Transforming Growth Factor-β Coreceptor Betaglycan: Proposed Mechanism for Potentiation of Receptor Complex Assembly and Signaling

[Image: see text] Transforming growth factor (TGF) β1, β2, and β3 (TGF-β1–TGF-β3, respectively) are small secreted signaling proteins that each signal through the TGF-β type I and type II receptors (TβRI and TβRII, respectively). However, TGF-β2, which is well-known to bind TβRII several hundred-fol...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Villarreal, Maria M., Kim, Sun Kyung, Barron, Lindsey, Kodali, Ravi, Baardsnes, Jason, Hinck, Cynthia S., Krzysiak, Troy C., Henen, Morkos A., Pakhomova, Olga, Mendoza, Valentín, O’Connor-McCourt, Maureen D., Lafer, Eileen M., López-Casillas, Fernando, Hinck, Andrew P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2016
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5551644/
https://ncbi.nlm.nih.gov/pubmed/27951653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00566
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