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Structural biology of betaglycan and endoglin, membrane-bound co-receptors of the TGF-beta family

Betaglycan and endoglin, membrane-bound co-receptors of the TGF-β family, are required to mediate the signaling of a select subset of TGF-β family ligands, TGF-β2 and InhA, and BMP-9 and BMP-10, respectively. Previous biochemical and biophysical methods suggested alternative modes of ligand binding...

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Bibliographic Details
Published in:Exp Biol Med (Maywood)
Main Authors: Kim, Sun Kyung, Henen, Morkos A, Hinck, Andrew P
Format: Artigo
Language:Inglês
Published: SAGE Publications 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6920675/
https://ncbi.nlm.nih.gov/pubmed/31601110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370219881160
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