Predicting the response to CTLA-4 blockade by longitudinal noninvasive monitoring of CD8 T cells

Immunotherapy using checkpoint-blocking antibodies against targets such as CTLA-4 and PD-1 can cure melanoma and non–small cell lung cancer in a subset of patients. The presence of CD8 T cells in the tumor correlates with improved survival. We show that immuno–positron emission tomography (immuno-PE...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:J Exp Med
Hauptverfasser: Rashidian, Mohammad, Ingram, Jessica R., Dougan, Michael, Dongre, Anushka, Whang, Katherine A., LeGall, Camille, Cragnolini, Juan J., Bierie, Brian, Gostissa, Monica, Gorman, James, Grotenbreg, Gijsbert M., Bhan, Atul, Weinberg, Robert A., Ploegh, Hidde L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2017
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5551571/
https://ncbi.nlm.nih.gov/pubmed/28666979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20161950
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge