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Predicting the response to CTLA-4 blockade by longitudinal noninvasive monitoring of CD8 T cells
Immunotherapy using checkpoint-blocking antibodies against targets such as CTLA-4 and PD-1 can cure melanoma and non–small cell lung cancer in a subset of patients. The presence of CD8 T cells in the tumor correlates with improved survival. We show that immuno–positron emission tomography (immuno-PE...
Gespeichert in:
| Veröffentlicht in: | J Exp Med |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5551571/ https://ncbi.nlm.nih.gov/pubmed/28666979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20161950 |
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