Predicting the response to CTLA-4 blockade by longitudinal noninvasive monitoring of CD8 T cells

Immunotherapy using checkpoint-blocking antibodies against targets such as CTLA-4 and PD-1 can cure melanoma and non–small cell lung cancer in a subset of patients. The presence of CD8 T cells in the tumor correlates with improved survival. We show that immuno–positron emission tomography (immuno-PE...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Exp Med
Egile Nagusiak: Rashidian, Mohammad, Ingram, Jessica R., Dougan, Michael, Dongre, Anushka, Whang, Katherine A., LeGall, Camille, Cragnolini, Juan J., Bierie, Brian, Gostissa, Monica, Gorman, James, Grotenbreg, Gijsbert M., Bhan, Atul, Weinberg, Robert A., Ploegh, Hidde L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Rockefeller University Press 2017
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5551571/
https://ncbi.nlm.nih.gov/pubmed/28666979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20161950
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