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Noninvasive imaging of tumor progression, metastasis, and fibrosis using a nanobody targeting the extracellular matrix
Extracellular matrix (ECM) deposition is a hallmark of many diseases, including cancer and fibroses. To exploit the ECM as an imaging and therapeutic target, we developed alpaca-derived libraries of “nanobodies” against disease-associated ECM proteins. We describe here one such nanobody, NJB2, speci...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6628802/ https://ncbi.nlm.nih.gov/pubmed/31068469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1817442116 |
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