Protective Role of Complement C3 Against Cytokine-Mediated β-Cell Apoptosis

Type 1 diabetes is a chronic autoimmune disease characterized by pancreatic islet inflammation and β-cell destruction by proinflammatory cytokines and other mediators. Based on RNA sequencing and protein–protein interaction analyses of human islets exposed to proinflammatory cytokines, we identified...

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Foilsithe in:Endocrinology
Main Authors: Dos Santos, Reinaldo S., Marroqui, Laura, Grieco, Fabio A., Marselli, Lorella, Suleiman, Mara, Henz, Stefan R., Marchetti, Piero, Wernersson, Rasmus, Eizirik, Decio L.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Endocrine Society 2017
Ábhair:
Research Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5551554/
https://ncbi.nlm.nih.gov/pubmed/28582497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2017-00104
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