Preparation and evaluation of enteric coated tablets of hot melt extruded lansoprazole

The objective of this work was to use hot-melt extrusion (HME) technology to improve the physiochemical properties of lansoprazole (LNS) to prepare stable enteric coated LNS tablets. For the extrusion process, we chose Kollidon(®) 12 PF (K12) polymeric matrix. Lutrol(®) F 68 was selected as the plas...

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Detalhes bibliográficos
Publicado no:Drug Dev Ind Pharm
Main Authors: Alsulays, Bader B., Kulkarni, Vijay, Alshehri, Sultan M., Almutairy, Bjad K., Ashour, Eman A., Morott, Joseph T., Alshetaili, Abdullah S., Park, Jun-Bom, Tiwari, Roshan V., Repka, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5551489/
https://ncbi.nlm.nih.gov/pubmed/27486807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/03639045.2016.1220567
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