DNMT1-maintained hypermethylation of Krüppel-like factor 5 involves in the progression of clear cell renal cell carcinoma

Clear cell renal cell carcinoma (ccRCC) is the major subtype of renal cell carcinoma (RCC) that is resistant to conventional radiation and chemotherapy. It is a challenge to explore effective therapeutic targets and drugs for this kind of cancer. Transcription factor Krüppel-like factor 5 (KLF5) exe...

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Publicat a:Cell Death Dis
Autors principals: Fu, Rong-Jie, He, Wei, Wang, Xiao-Bo, Li, Lei, Zhao, Huan-Bin, Liu, Xiao-Ye, Pang, Zhi, Chen, Guo-Qiang, Huang, Lei, Zhao, Ke-Wen
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550868/
https://ncbi.nlm.nih.gov/pubmed/28749461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.323
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