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DNMT1-maintained hypermethylation of Krüppel-like factor 5 involves in the progression of clear cell renal cell carcinoma

Clear cell renal cell carcinoma (ccRCC) is the major subtype of renal cell carcinoma (RCC) that is resistant to conventional radiation and chemotherapy. It is a challenge to explore effective therapeutic targets and drugs for this kind of cancer. Transcription factor Krüppel-like factor 5 (KLF5) exe...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Fu, Rong-Jie, He, Wei, Wang, Xiao-Bo, Li, Lei, Zhao, Huan-Bin, Liu, Xiao-Ye, Pang, Zhi, Chen, Guo-Qiang, Huang, Lei, Zhao, Ke-Wen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550868/
https://ncbi.nlm.nih.gov/pubmed/28749461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.323
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