DNMT1-maintained hypermethylation of Krüppel-like factor 5 involves in the progression of clear cell renal cell carcinoma

Clear cell renal cell carcinoma (ccRCC) is the major subtype of renal cell carcinoma (RCC) that is resistant to conventional radiation and chemotherapy. It is a challenge to explore effective therapeutic targets and drugs for this kind of cancer. Transcription factor Krüppel-like factor 5 (KLF5) exe...

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Détails bibliographiques
Publié dans:Cell Death Dis
Auteurs principaux: Fu, Rong-Jie, He, Wei, Wang, Xiao-Bo, Li, Lei, Zhao, Huan-Bin, Liu, Xiao-Ye, Pang, Zhi, Chen, Guo-Qiang, Huang, Lei, Zhao, Ke-Wen
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2017
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550868/
https://ncbi.nlm.nih.gov/pubmed/28749461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.323
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