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Preeclampsia is associated with hypermethylation of IGF-1 promoter mediated by DNMT1

Previous studies have demonstrated a dynamic epigenetic regulation of genes expression in placenta trophoblasts and a dynamic imbalance of DNA methylation and hydroxymethylation. Reduced IGF-1 has been observed in preeclampsia. This study was to investigate the interactive roles between IGF-1 and th...

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Bibliographic Details
Published in:Am J Transl Res
Main Authors: Ma, Min, Zhou, Qiong-Jie, Xiong, Yu, Li, Bin, Li, Xiao-Tian
Format: Artigo
Language:Inglês
Published: e-Century Publishing Corporation 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5801344/
https://ncbi.nlm.nih.gov/pubmed/29422991
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