FOXC1 promotes HCC proliferation and metastasis by Upregulating DNMT3B to induce DNA Hypermethylation of CTH promoter

BACKGROUND: Forkhead box C1 (FOXC1), as a member of the FOX family, is important for promote HCC invasion and metastasis. FOX family protein lays a pivotal role in metabolism. ROS is involved in tumor progression and is associated with the expression of lots of transcription factors. We next explore...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Lin, Zhuoying, Huang, Wenjie, He, Qin, Li, Dongxiao, Wang, Zhihui, Feng, Yangyang, Liu, Danfei, Zhang, Tongyue, Wang, Yijun, Xie, Meng, Ji, Xiaoyu, Sun, Mengyu, Tian, Dean, Xia, Limin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7852227/
https://ncbi.nlm.nih.gov/pubmed/33522955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-021-01829-6
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