IGF1-mediated HOXA13 overexpression promotes colorectal cancer metastasis through upregulating ACLY and IGF1R

Metastasis is the major reason for the high mortality of colorectal cancer (CRC) patients and its molecular mechanism remains unclear. Here, we report a novel role of Homeobox A13 (HOXA13), a member of the Homeobox (HOX) family, in promoting CRC metastasis. The elevated expression of HOXA13 was posi...

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Xehetasun bibliografikoak
Argitaratua izan da:Cell Death Dis
Egile Nagusiak: Qiao, Chenyang, Huang, Wenjie, Chen, Jie, Feng, Weibo, Zhang, Tongyue, Wang, Yijun, Liu, Danfei, Ji, Xiaoyu, Xie, Meng, Sun, Mengyu, Fan, Daiming, Wu, Kaichun, Xia, Limin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2021
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8169856/
https://ncbi.nlm.nih.gov/pubmed/34075028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03833-2
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