IGF1-mediated HOXA13 overexpression promotes colorectal cancer metastasis through upregulating ACLY and IGF1R

Metastasis is the major reason for the high mortality of colorectal cancer (CRC) patients and its molecular mechanism remains unclear. Here, we report a novel role of Homeobox A13 (HOXA13), a member of the Homeobox (HOX) family, in promoting CRC metastasis. The elevated expression of HOXA13 was posi...

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發表在:Cell Death Dis
Main Authors: Qiao, Chenyang, Huang, Wenjie, Chen, Jie, Feng, Weibo, Zhang, Tongyue, Wang, Yijun, Liu, Danfei, Ji, Xiaoyu, Xie, Meng, Sun, Mengyu, Fan, Daiming, Wu, Kaichun, Xia, Limin
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2021
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8169856/
https://ncbi.nlm.nih.gov/pubmed/34075028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03833-2
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