miR-181d and c-myc-mediated inhibition of CRY2 and FBXL3 reprograms metabolism in colorectal cancer

Colorectal cancer (CRC) is the second major cause of tumor-related deaths. MicroRNAs (miRNAs) have pivotal roles in CRC progression. Here, we describe the effect of miR-181d on CRC cell metabolism and underlying molecular mechanism. Our data firmly demonstrated that knockdown of miR-181d suppressed...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Guo, Xiaofeng, Zhu, Yuekun, Hong, Xinya, Zhang, Mukun, Qiu, Xingfeng, Wang, Zhenfa, Qi, Zhongquan, Hong, Xuehui
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550850/
https://ncbi.nlm.nih.gov/pubmed/28749470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.300
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